Cáncer de cérvix uterino

Enfermedad localmente avanzada

Paclitaxel + Cisplatino + Ifosfamida neoadyuvante en enfermedad localmente avanzada (Estadíos Ib, IIb de menos de 7 cm), seguida por histerectomía radical - TIP

- Benedetti-Panici P, Greggi S, Colombo A, et al. Neoadjuvant Chemotherapy and Radical Surgery Versus Exclusive Radiotherapy in Locally Advanced Squamous Cell Cervical Cancer: Results From the Italian Multicenter Randomized Study. J Clin Oncol 2002 20: 179-188

Metastásico

Cisplatino + Topotecán - CisTopotecán

- Long HJ, Bundy BN, Grendys E, et al. Randomized Phase III Trial of Cisplatin With or Without Topotecan in Carcinoma of the Uterine Cervix: A Gynecologic Oncology Group Study. J Clin Oncol 2005 23: 4626-4633